7nut | pdb_00007nut

Crystal structure of human AMDHD2 in complex with Zn and GlcN6P

spinqualitylabelsall models 7nut, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7nut is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GLP, ZN Activity: N-acetylglucosamine-6-phosphate deacetylase, with EC number 3.5.1.25 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [NAGA_HUMAN] Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.

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