2w3v | pdb_00002w3v

MYCOBACTERIUM AVIUM DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND TRIMETHOPRIM

spinqualitylabelsall models 2w3v, resolution 1.89Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2w3v is a 1 chain structure with sequence from "bacillus_tuberculosis_gallinarum"_sternberg_1892 "bacillus tuberculosis gallinarum" sternberg 1892. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: NDP, TOP Related: 2w3w Activity: Dihydrofolate reductase, with EC number 1.5.1.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [O30463_MYCAV] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Dihydrofolate reductase 3D structures

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