6uf2 | pdb_00006uf2

NMR structure of biofilm-related Se0862 from Synechococcus elongatus

spinqualitylabelsall models 6uf2, 10 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6uf2 is a 1 chain structure with sequence from Anacystis nidulans r2. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: Synpcc7942_0862 (Anacystis nidulans R2) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed Biofilms are accumulations of microorganisms embedded in extracellular matrices that protect against external factors and stressful environments. Cyanobacterial biofilms are ubiquitous and have potential for treatment of wastewater and sustainable production of biofuels. But the underlying mechanisms regulating cyanobacterial biofilm formation are unclear. Here, we report the solution NMR structure of a protein, Se0862, conserved across diverse cyanobacterial species and involved in regulation of biofilm formation in the cyanobacterium Synechococcus elongatus PCC 7942. Se0862 is a class alpha+beta protein with alphaalphabetabetabetabetaalphaalpha topology and roll architecture, consisting of a four-stranded beta-sheet that is flanked by four alpha-helices on one side. Conserved surface residues constitute a hydrophobic pocket and charged regions that are likely also present in Se0862 orthologs. Solution NMR structure of Se0862, a highly conserved cyanobacterial protein involved in biofilm formation.,Zhang N, Chang YG, Tseng R, Ovchinnikov S, Schwarz R, LiWang A Protein Sci. 2020 Nov;29(11):2274-2280. doi: 10.1002/pro.3952. Epub 2020 Oct 24. PMID:32949024 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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