3k2z | pdb_00003k2z

Crystal structure of a LexA protein from Thermotoga maritima

spinqualitylabelsall models 3k2z, resolution 1.37Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3k2z is a 2 chain structure with sequence from Atcc 43589. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GOL Gene: lexA, TM_1082 (ATCC 43589) Activity: Repressor lexA, with EC number 3.4.21.88 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [LEXA_THEMA] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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