1hxa | pdb_00001hxa

CRYSTAL STRUCTURE OF TEAS W273S FORM 2

spinqualitylabelsall models 1hxa, resolution 2.32Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1hxa is a 1 chain structure with sequence from American tobacco. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: FHP, MG Related: 5eas, 5eat, 1hx9 Activity: Aristolochene synthase, with EC number 4.2.3.9 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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