2xzz | pdb_00002xzz

Crystal structure of the human transglutaminase 1 beta-barrel domain

spinqualitylabelsall models 2xzz, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2xzz is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Activity: Protein-glutamine gamma-glutamyltransferase, with EC number 2.3.2.13 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [TGM1_HUMAN] Lamellar ichthyosis;Self-healing collodion baby;Bathing suit ichthyosis;Acral self-healing collodion baby;Congenital non-bullous ichthyosiform erythroderma. The disease is caused by mutations affecting the gene represented in this entry. Function [TGM1_HUMAN] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum.

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