2h52 | pdb_00002h52

Crystal structure of human bisphosphoglycerate mutase complex with 3-phosphoglycerate (18 days)

spinqualitylabelsall models 2h52, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2h52 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 3PG, HAI Related: 2h4x, 2h4z Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [PMGE_HUMAN] Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) [MIM:222800]. A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis. Function [PMGE_HUMAN] Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activities. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Phosphoglycerate mutase 3D structures

Proteopedia Page Contributors and Editors (what is this?)

OCA