7ck4 | pdb_00007ck4

Structural and functional analysis of small heat shock protein from Synechococcus phage S-ShM2

spinqualitylabelsall models 7ck4, resolution 7.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7ck4 is a 6 chain structure with sequence from Cyanophage 8102-4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: hsp20, SShM2_166 (Cyanophage 8102-4) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The structures of a cyanophage small heat shock protein (sHSP) were determined as octahedrons of 24-mers and 48-mers and as icosahedrons of 60-mers. An N-terminal deletion construct of an 18 kDa sHSP of Synechococcus sp. phage S-ShM2 crystallized as a 24-mer and its structure was determined at a resolution of 7 A. The negative stain electron microscopy (EM) images showed that the full-length protein is a mixture of a major population of larger and a minor population of smaller cage-like particles. Their structures have been determined by electron cryomicroscopy 3D image reconstruction at a resolution of 8 A. The larger particles are 60-mers with icosahedral symmetry and the smaller ones are 48-mers with octahedral symmetry. These structures are the first of the viral/phage origin and the 60-mer is the largest and the first icosahedral assembly to be reported for sHSPs. Multiple nanocages of a cyanophage small heat shock protein with icosahedral and octahedral symmetries.,Biswas S, Garg P, Dutta S, Suguna K Sci Rep. 2021 Oct 25;11(1):21023. doi: 10.1038/s41598-021-00172-2. PMID:34697325 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Heat Shock Protein structures

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