1hsn | pdb_00001hsn

THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA

spinqualitylabelsall models 1hsn, 49 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1hsn is a 1 chain structure with sequence from Cho cell lines. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BME Related: 1hsm Gene: INSERT DERIVED BY PCR (CHO cell lines) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [HMGB1_CRIGR] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also High mobility group protein

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