1ufn | pdb_00001ufn

Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)

spinqualitylabelsall models 1ufn, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1ufn is a 1 chain structure with sequence from Lk3 transgenic mice. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: RIKEN cDNA 5830484A20 (LK3 transgenic mice) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN Disease [SP110_MOUSE] Defects in Sp110 are a cause of severely impaired resistance to infection by M.tuberculosis. Function [SP110_MOUSE] May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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