3kw8 | pdb_00003kw8

Two-domain laccase from Streptomyces coelicolor at 2.3 A resolution

spinqualitylabelsall models 3kw8, resolution 2.29Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3kw8 is a 1 chain structure with sequence from "actinomyces_coelicolor"_(muller_1908)_lieske_1921 "actinomyces coelicolor" (muller 1908) lieske 1921. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CU, FE, NA, PG4, PGE Related: 3cg8 Gene: SC4C6.22 ("Actinomyces coelicolor" (Muller 1908) Lieske 1921) Activity: Laccase, with EC number 1.10.3.2 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The paper reports the structure of the small laccase from Streptomyces coelicolor determined from a crystal soaked with potassium hexacyanoferrate [K4Fe(CN)6]. The decolorization of the natively blue crystal observed upon soaking indicates the reduction of the enzyme in the crystal. The ligand binds between laccase molecules and stabilizes the crystal. The increased diffraction limit of the diffraction data collected from this crystal enabled the refinement of the small laccase structure at 2.3 A resolution, which is the highest resolution obtained to date. Structure of laccase from Streptomyces coelicolor after soaking with potassium hexacyanoferrate and at an improved resolution of 2.3 A.,Skalova T, Duskova J, Hasek J, Stepankova A, Koval T, Ostergaard LH, Dohnalek J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jan 1;67(Pt, 1):27-32. Epub 2010 Dec 21. PMID:21206017 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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