3p4u | pdb_00003p4u

Crystal structure of active caspase-6 in complex with Ac-VEID-CHO inhibitor

spinqualitylabelsall models 3p4u, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3p4u is a 6 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. NonStd Res: ACE, ASJ, CAS Related: 3p45 Gene: CASP6, MCH2 (HUMAN) Activity: Caspase-6, with EC number 3.4.22.59 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. See Also Caspase 3D structures

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