3psn | pdb_00003psn

Crystal structure of mouse VPS29 complexed with Mn2+

spinqualitylabelsall models 3psn, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3psn is a 2 chain structure with sequence from Lk3 transgenic mice. This structure supersedes the now removed PDB entry 3lh7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MN Related: 1w24, 1x2x, 1z2w, 2a22, 2r17, 3pso Gene: Vps29 (LK3 transgenic mice) Activity: Phosphoserine phosphatase, with EC number 3.1.3.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [VPS29_MOUSE] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). See Also Vacuolar protein sorting-associated protein 3D structures

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