3qgp | pdb_00003qgp

Crystal structure of IsdI in complex with heme and cyanide

spinqualitylabelsall models 3qgp, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3qgp is a 2 chain structure with sequence from Staan. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CYN, HEM, MG Gene: isdI, SA0160 (STAAN) Activity: Heme oxygenase, with EC number 1.14.99.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [HDOX2_STAAN] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.[HAMAP-Rule:MF_01272] See Also Heme oxygenase 3D structures Monooxygenase 3D structures

Proteopedia Page Contributors and Editors (what is this?)

OCA