Stringent starvation protein

spinqualitylabelsall models SspA (pink, yellow) complex with MglA (green, grey), ppGpp, glycerol, PEG400 (PDB ID 5u51) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Stringent starvation protein A (SspA) is an RNA polymerase-associated protein involved in nucleotide metabolism acid tolerance and virulence of bacteria. In Francisella virulence, a set of regulators are essensial for its activation. These regulators include the heterdimer of SspA, macrophage growth locus A (MglA) and pathogenicity island gene regulator (PigR). The guanosine-tetraphosphate (ppGpp) is also involved in coordinating the virulence. == Disease =s Structural highlights This is a sample scene created with SAT to color by Group, and another to make a transparent representation of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

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Michal Harel, Alexander Berchansky