4bvu | pdb_00004bvu

Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate

spinqualitylabelsall models 4bvu, resolution 2.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4bvu is a 3 chain structure with sequence from Homo sapiens and Shigella flexneri. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [OSPG_SHIFL] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria. Prevents or at least delays host phospho-NF-kappa-B inhibitor alpha (NFKBIA) degradation. Does not phosphorylate E2 enzymes. See Also 3D structures of ubiquitin conjugating enzyme

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