Structural highlights
Function
[NIRDL_HYDTT] Involved in heme d1 biosynthesis. Catalyzes the decarboxylation of siroheme into didecarboxysiroheme. Siroheme is probably decarboxylated to monodecarboxysiroheme, which is in turn decarboxylated to didecarboxysiroheme.[1]
References
- ↑ Haufschildt K, Schmelz S, Kriegler TM, Neumann A, Streif J, Arai H, Heinz DW, Layer G. The crystal structure of siroheme decarboxylase in complex with iron-uroporphyrin III reveals two essential histidine residues. J Mol Biol. 2014 Jul 29. pii: S0022-2836(14)00369-6. doi:, 10.1016/j.jmb.2014.07.021. PMID:25083922 doi:https://dx.doi.org/10.1016/j.jmb.2014.07.021
