6zc8 | pdb_00006zc8

Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling

spinqualitylabelsall models 6zc8, resolution 2.76Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6zc8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: QEK Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [DVL3_HUMAN] Autosomal dominant Robinow syndrome. The disease is caused by variants affecting the gene represented in this entry. Function [DVL3_HUMAN] Involved in the signal transduction pathway mediated by multiple Wnt genes.[UniProtKB:Q61062]

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