7tti

Human KCC1 bound with VU0463271 In an outward-open state

spinqualitylabelsall models 7tti, resolution 3.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7tti is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: JUX, NAG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [S12A4_HUMAN] Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.

Proteopedia Page Contributors and Editors (what is this?)

OCA