7x5n | pdb_00007x5n

Crystal structure of E. faecium SHMT in complex with (+)-SHIN-1 and PLP-Ser

spinqualitylabelsall models 7x5n, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7x5n is a 2 chain structure with sequence from Enterococcus faecium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 5M5, PLS Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [A0A133CK16_ENTFC] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.[HAMAP-Rule:MF_00051]

Proteopedia Page Contributors and Editors (what is this?)

OCA