8hg1 | pdb_00008hg1

The structure of MPXV polymerase holoenzyme in replicating state

spinqualitylabelsall models 8hg1, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8hg1 is a 5 chain structure with sequence from Monkeypox virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MG, TTP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q5IXS4_MONPV Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.[ARBA:ARBA00025092]

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