7pwx | pdb_00007pwx

Structure of Mycobacterium tuberculosis dUTPase at 2.75A.

spinqualitylabelsall models 7pwx, resolution 2.75Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7pwx is a 12 chain structure with sequence from Mycobacterium tuberculosis H37Rv and Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: EDO, PEG, TRS Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DUT_MYCTU This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116]

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