Troponin

spinqualitylabelsall models Chicken troponin: subunit T (dark green), subunit I (wheat), subunit C (pink) complex with Mg+2 ion (green) 1yv0 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Troponin (Tn) is a regulatory protein in muscle contraction. It contains 3 subunits: TnC causes conformational change in TnI when it binds to calcium ions. For more details on TnC see Role of Troponin C in decreased muscle sensitivity to calcium Human Cardiac Troponin C Human Cardiac Troponin C in complex with the Green Tea Polyphenol TnT binds to tropomyosin. TnI binds to actin which is found in thin muscle filaments. See Human Cardiac Troponin I Disease Mutations in TnI and TnT are associated with hypertrophic cardiomyopathy. 3D Structures of Troponin Troponin 3D structures

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Alexander Berchansky, Joel L. Sussman, Michal Harel