7qqe | pdb_00007qqe

Nuclear factor one X - NFIX in P41212

spinqualitylabelsall models 7qqe, resolution 3.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7qqe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: EPE, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease NFIX_HUMAN 19p13.3 microduplication syndrome;Malan overgrowth syndrome;Marshall-Smith syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function NFIX_HUMAN Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

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