4o38 | pdb_00004o38

Crystal structure of the human cyclin G associated kinase (GAK)

spinqualitylabelsall models 4o38, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4o38 is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3ll6. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GOL, MSE, SIN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GAK_HUMAN Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

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