7vzg | pdb_00007vzg

Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c (the larger form)

spinqualitylabelsall models 7vzg, resolution 2.61Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7vzg is a 14 chain structure with sequence from Chloracidobacterium thermophilum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 2GO, 84Q, 85I, 85N, BCL, CA, CLA, HEC, LYC, SF4, UNL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function G2LDR4_CHLTF Publication Abstract from PubMed Photosynthesis converts light energy to chemical energy to fuel life on earth. Light energy is harvested by antenna pigments and transferred to reaction centers (RCs) to drive the electron transfer (ET) reactions. Here, we present cryo-electron microscopy (cryo-EM) structures of two forms of the RC from the microaerophilic Chloracidobacterium thermophilum (CabRC): one containing 10 subunits, including two different cytochromes; and the other possessing two additional subunits, PscB and PscZ. The larger form contained 2 Zn-bacteriochlorophylls, 16 bacteriochlorophylls, 10 chlorophylls, 2 lycopenes, 2 hemes, 3 Fe(4)S(4) clusters, 12 lipids, 2 Ca(2+) ions and 6 water molecules, revealing a type I RC with an ET chain involving two hemes and a hybrid antenna containing bacteriochlorophylls and chlorophylls. Our results provide a structural basis for understanding the excitation energy and ET within the CabRC and offer evolutionary insights into the origin and adaptation of photosynthetic RCs. Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c.,Dong S, Huang G, Wang C, Wang J, Sui SF, Qin X Nat Commun. 2022 Dec 14;13(1):7745. doi: 10.1038/s41467-022-35460-6. PMID:36517472 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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