2m2b | pdb_00002m2b
From Proteopedia
NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens
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Structural highlights
DiseaseRBM10_HUMAN TARP syndrome. TARP syndrome (TARPS) [MIM:311900: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.[1] FunctionRBM10_HUMAN May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).[2] References
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This page was last modified 13:25, 22 February 2023.