8ar2 | pdb_00008ar2

Solution structure of TLR5 transmembrane and cytoplasmic juxtamembrane regions

spinqualitylabelsall models 8ar2 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ar2 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease TLR5_HUMAN Disease susceptibility is associated with variations affecting the gene represented in this entry. Function TLR5_HUMAN Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

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