8fd7 | pdb_00008fd7

Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with gabapentin

spinqualitylabelsall models 8fd7, resolution 3.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8fd7 is a 3 chain structure with sequence from Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CA, CLR, GBN, NA, NAG, WO9, YSW Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CA2D1_RABIT The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling.

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