7x8x | pdb_00007x8x

structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease

spinqualitylabelsall models 7x8x, resolution 3.24Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7x8x is a 56 chain structure with sequence from Mycobacterium tuberculosis, Mycobacterium tuberculosis CDC1551 and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: AI4, BEZ Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CLPP2_MYCTO Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.[HAMAP-Rule:MF_00444]

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