8ebt | pdb_00008ebt

XPA repositioning Core7 of TFIIH relative to XPC-DNA lesion (Cy5)

spinqualitylabelsall models 8ebt, resolution 3.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ebt is a 10 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CA, SF4, VM6, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TF2H2_HUMAN Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.

Proteopedia Page Contributors and Editors (what is this?)

OCA