7xlf | pdb_00007xlf

Crystal structure of CH3-THF complex of methylenetetrahydrofolate reductase from Sphingobium sp. SYK-6

spinqualitylabelsall models 7xlf, resolution 1.85Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7xlf is a 2 chain structure with sequence from Sphingobium sp. SYK-6. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: C2F, FAD, PEG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function METF_SPHSK Catalyzes the NADH-dependent reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. Is required to provide the methyl group necessary for methionine synthetase to convert homocysteine to methionine; the methyl group is given by 5-methyltetrahydrofolate (By similarity). Is required for Sphingobium SYK-6 to grow on vanillate or syringate as the sole source of carbon (Ref.3).[UniProtKB:P0AEZ1][REFERENCE:3]

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