Histone acetyltransferase 3D structures
From Proteopedia
Revision as of 07:49, 21 May 2023 by Michal Harel (talk | contribs)
3D Structures of histone acetyltransferase
Updated on 21-May-2023
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- Histone acetyltransferase; Human domains – WH 100-182; DPF 194-323; HAT 170-458; catalytic 497-662; bromodomain 729-837;
- 1f68 – hHAT bromodomain (mutant) – human – NMR
- 1n72 - hHAT bromodomain – NMR
- 3d7c - hHAT bromodomain
- 3gg3 - hHAT PCAF bromodomain
- 2ou2 - hHAT HTATIP
- 2eko – hHAT HTATIP histone tail-binding domain - NMR
- 1z4r – hHAT catalytic domain
- 3toa - hHAT Myst1 HAT domain
- 3tob - hHAT Myst1 HAT domain (mutant)
- 2rc4 – hHAT Myst3 acetyltransferase domain
- 5trm - hHAT KAT2A catalytic domain
- 4nsq - hHAT KAT2B
- 4qqg - hHAT KAT5 N terminal
- 2ln0 - hHAT KAT6A
- 4ljn - hHAT KAT6A double PHD finger
- 8e4v - hHAT KAT6B WH domain - NMR
- 5wci - hHAT KAT8 HAT domain
- 7cmr - hHAT KAT8 1-458
- 5j8c, 5j8f - hHAT KAT8 HAT domain (mutant)
- 7by1 - mHAT KAT2A N-terminal 67-378 - mouse
- 1qso - yHAT HPA2 – yeast
- 3to7 – yHAT Esa1
- 2rnz – yHAT Esa1 chromodomain – NMR
- 2ro0 - yHAT Esa1 knotted Tudor domain – NMR
- 1ygh – yHAT HAT domain
- 6s1l – fyHAT B subunit 2 – fission yeast
- 2qec – HAT HPA2 (mutant) – Corynebacterium glutamicum
- 6ia8, 6iad, 6iaz - HAT – Methanocaldococcus infernus
- 6if4 - HAT – Trypanosoma brucei
- 7bwz, 7bx0, 7bx1, 7bxw, 7c3o - HAT RTT109 – Candida albicans
- Histone acetyltransferase binary complexes
- 1wug, 1wum – hHAT PCAF + small ligand
- 1zs5 – hHAT bromodomain + inhibitor – NMR
- 2ozu - hHAT MYST3 catalytic domain + acetyl-CoA
- 2p0w - hHAT 1 catalytic domain + histone H4 peptide
- 2rnw, 2rnx - hHAT PCAF bromodomain + histone H3 peptide - NMR
- 5h84 - hHAT KAT2A catalytic domain + propionyl CoA
- 5h86 - hHAT KAT2A catalytic domain + butyryl CoA
- 5trl - hHAT KAT2A catalytic domain + succinyl CoA
- 5mlj, 6j3p - hHAT KAT2A bromodomain + inhibitor
- 5lvq, 5lvr, 5fdz, 5fe0, 5fe1, 5fe2, 5fe3, 5fe4, 5fe5, 5fe6, 5fe7, 5fe8, 5fe9, 5mkx - hHAT KAT2B bromodomain + inhibitor
- 4dnc – hHAT KAT8 HAT domain + male-specific lethal 1 homolog
- 3v43, 4lk9, 4lka, 4llb, 5b75, 5b76, 5b77, 5b78, 6lsb - hHAT KAT6A + H3.1 peptide
- 7y43, 8h7a - hHAT KAT6A + DNA
- 5u2j, 6oie - hHAT KAT6B + H3K14BU peptide
- 5gk9, 6maj, 6mak, 7d0o - hHAT KAT7 + BRD1
- 4dnc – hHAT KAT8 HAT domain + male-specific lethal 1 homolog
- 6ct2, 6ba2 – hHAT KAT8 HAT domain + inhibitor
- 6oin, 6oio, 6oip, 6oir, 6owh, 6owi, 6pd8, 6pd9, 6pda, 6pdb, 6pdc, 6pdd, 6pde, 6pdf, 6pdg – hHAT KAT8 HAT domain (mutant) + inhibitor
- 5h86, 6ba4 - hHAT KAT8 HAT domain + acetyl CoA
- 7kpy - hHAT 617-732 + inhibitor
- 7qgs - hHAT 330-440 + MRG-1
- 5ml0 - mHAT KAT2B bromodomain + inhibitor
- 1bob – yHAT 1 + acetyl-CoA
- 1qsm – yHAT HPA2 + acetyl-CoA
- 1fy7, 1mja - yHAT Esa1 + CoA
- 3to6 - yHAT Esa1 + H4 peptide
- 4psw - yHAT B + H4 peptide
- 1e6i - yHAT bromodomain + H4 peptide
- 1mj9, 3to9 - yHAT Esa1 (mutant) + CoA
- 1mjb - yHAT Esa1 (mutant) + acetyl-CoA
- 3qm0 - yHAT RTT109 (mutant) + acetyl-CoA
- 3q35, 3q66, 3q68 – yHAT RTT109 + vacuolar protein sorting-associated protein 75
- 6s1r – fyHAT B subunit 2 + histone H4
- 6s29 – fyHAT B subunit 2 + Mis19
- 5gcn – TtHAT Gcn5 + CoA – Tetrahymena thermophila - NMR
- 5tpx - HAT GCN5 + probe – Plasmodium falciparum
- Histone acetyltransferase ternary complexes
- 6vo5 – hHAT B catalytic subunit + histone H4 + CoA derivative
- 7d0p, 7d0q, 7d0r, 7d0s - hHAT KAT7 + BRD1 + CoA derivative
- 3q33 – yHAT RTT109 + vacuolar protein sorting-associated protein 75 + histone H3 peptide
- 7xay – yHAT1 + HAT2 + ASF1 + histone H3 + histone H4
- 6o22 - yHAT RTT109 + vacuolar protein sorting-associated protein 75 + ASF1 + histone H3.2 + histone H4 – NMR
- 4psx - yHAT B + H3 peptide + H4 peptide
- 5j9q, 5j9t, 5j9u, 5j9w - yHAT Esa1 (mutant) + chromatin modification-related protein + enhancer of polycomb-like protein
- 6cw3, 6cw2 - yHAT GCN5 residues 67-316 + transcriptional adaptor + antibody
- 1q2c - TtHAT Gcn5 + CoA + histone H4 peptide
- 1q2d - TtHAT Gcn5 + CoA + p53 peptide
- 6vo5 – hHAT B catalytic subunit + histone H4 + CoA derivative
- Histone acetyltransferase P300; domains – core domain residues 1043-1519; bromodomain residues 1040-1161; acetyltransferase domain residues 1287-1664; TAZ2 domain 1723-1836:
- 3i3j – hHAT P300 bromodomain
- 7uge, 7ugi, 7ugl - hHAT P300 bromodomain + inhibitor
- 3io2 – hHAT P300 TAZ2 domain
- 6fgn, 6fgs - hHAT TAZ2 domain - NMR
- 2mzd - hHAT TAZ2 domain (mutant) + p53 peptide - NMR
- 4bhw - hHAT P300 core (mutant)
- 6k4n - hHAT P300 bromodomain+acetyltransferase domains – Cryo EM
- 2mh0 - hHAT P300 TAZ2 + transcription factor ITF-1
- 2mh0, 2k8f - hHAT P300 TAZ2 (mutant) + p53 peptide
- 4pzr, 4pzs - hHAT P300 acetyltransferase domain (mutant) + acetyl CoA
- 4pzt - hHAT P300 acetyltransferase domain (mutant) + acetonyl CoA
- 5lkt - hHAT P300 residues 1581-1666 + butyryl CoA
- 5lku - hHAT P300 core + CoA
- 5lkx - hHAT P300 core (mutant) + propionyl CoA
- 5lkz - hHAT P300 core (mutant) + crotonyl CoA
- 3biy – hHAT P300 acetyltransferase domain + lysine CoA derivative
- 5kj2, 7lje - hHAT P300 acetyltransferase domain + inhibitor
- 6pf1, 6v8b, 6v8k, 6v8n, 6v90, 7ss8, 7ssk, 7szq, 7vhy, 7vhz, 7vi0, 8gzc - hHAT P300 acetyltransferase domain (mutant) + inhibitor
- 6pgu - hHAT P300 acetyltransferase domain (mutant) + inhibitor + CoA
- 6gyr - hHAT P300 core+acetyltransferase domains + lysine CoA derivative
- 5xzc - hHAT P300 core+acetyltransferase domains + p53
- 5bt3, 5nu5, 5lpk, 5lpm - hHAT P300 bromodomain + inhibitor
- 6gyt - hHAT P300 bromodomain + histone H4 peptide
- 7w9v, 8hag, 8hah, 8hai, 8haj, 8hak - hHAT P300 1098-1836 + nucleosome – Cryo EM
- 3p57 - hHAT P300 TAZ2 domain + myocyte-specific enhancer factor 2A + DNA
- 3i3j – hHAT P300 bromodomain
