7zug | pdb_00007zug

Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain

spinqualitylabelsall models 7zug, resolution 1.07Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7zug is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CL, IOD, NA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease HNRH1_HUMAN Precursor T-cell acute lymphoblastic leukemia. Function HNRH1_HUMAN This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).

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