8dvc | pdb_00008dvc

Receptor ShHTL5 from Striga hermonthica in complex with strigolactone agonist GR24

spinqualitylabelsall models 8dvc, resolution 2.64Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8dvc is a 5 chain structure with sequence from Striga hermonthica. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CL, EDO, SO4, TZU Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function A0A0M5I297_STRHE Publication Abstract from PubMed Strigolactones (SLs) regulate many aspects of plant development, but ambiguities remain about how this hormone is perceived because SL-complexed receptor structures do not exist. We find that when SL binds the Striga receptor, ShHTL5, a series of conformational changes relative to the unbound state occur, but these events are not sufficient for signalling. Ligand-complexed receptors, however, form internal tunnels that posit an explanation for how SL exits its receptor after hydrolysis. Structural analysis of a hormone-bound Striga strigolactone receptor.,Arellano-Saab A, Skarina T, Xu Z, McErlean CSP, Savchenko A, Lumba S, Stogios PJ, McCourt P Nat Plants. 2023 Jun 1. doi: 10.1038/s41477-023-01423-y. PMID:37264151 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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