2m8a | pdb_00002m8a

2'F-ANA/2'F-RNA alternated sequences

spinqualitylabelsall models 2m8a Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2m8a is a 2 chain structure. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: AF2, CFL, CFZ, GF2, TAF, UFT Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed Polarizing CHO hydrogen bonds: The structure of oligonucleotides containing alternating and contiguous tracts of 2'F-RNA and 2'F-ANA nucleotides reveals that nonconventional FCHO hydrogen bonds have a strong stabilizing effect on 2'-fluorinated duplexes. Backbone FCHO Hydrogen Bonds in 2'F-Substituted Nucleic Acids.,Martin-Pintado N, Deleavey GF, Portella G, Campos-Olivas R, Orozco M, Damha MJ, Gonzalez C Angew Chem Int Ed Engl. 2013 Sep 23. doi: 10.1002/anie.201305710. PMID:24115468 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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