6qs0 | pdb_00006qs0

NMR structure of BB_A03, Borrelia burgdorferi outer surface lipoprotein

spinqualitylabelsall models 6qs0 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6qs0 is a 1 chain structure with sequence from Borreliella burgdorferi B31. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Y2503_BORBU Publication Abstract from PubMed BBA03 is a Borrelia burgdorferi outer surface lipoprotein encoded on one of the most conserved plasmids in Borrelia genome, linear plasmid 54 (lp54). Although many of its genes have been identified as contributing or essential for spirochete fitness in vivo, the majority of the proteins encoded on this plasmid have no known function and lack homologs in other organisms. In this paper, we report the solution NMR structure of the B. burgdorferi outer surface lipoprotein BBA03, which is known to provide a competitive advantage to the bacteria during the transmission from tick vector to mammalian host. BBA03 shows structural homology to other outer surface lipoproteins reflecting their genetic and evolutionary relatedness. Analysis of the structure reveals a pore in BBA03, which could potentially bind lipids. Structural and Functional Analysis of BBA03, Borrelia burgdorferi Competitive Advantage Promoting Outer Surface Lipoprotein.,Fridmanis J, Bobrovs R, Brangulis K, Tars K, Jaudzems K Pathogens. 2020 Oct 9;9(10):826. doi: 10.3390/pathogens9100826. PMID:33050189 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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