1p1y | pdb_00001p1y

Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)

spinqualitylabelsall models 1p1y, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1p1y is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BRU, CBR, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed DNA has proved to be a versatile material for the rational design and assembly of nanometer scale objects. Here we report the crystal structure of a continuous three-dimensional DNA lattice formed by the self-assembly of a DNA 13-mer. The structure consists of stacked layers of parallel helices with adjacent layers linked through parallel-stranded base pairing. The hexagonal lattice geometry contains solvent channels that appear large enough to allow 3'-linked guest molecules into the crystal. We have successfully used these parallel base pairs to design and produce crystals with greatly enlarged solvent channels. This lattice may have applications as a molecular scaffold for structure determination of guest molecules, as a molecular sieve, or in the assembly of molecular electronics. Predictable non-Watson-Crick base pairs, like those described here, may present a new tool in structural DNA nanotechnology. Crystal structure of a continuous three-dimensional DNA lattice.,Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC Chem Biol. 2004 Aug;11(8):1119-26. PMID:15324813 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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