5czu | pdb_00005czu

Crystal structure of FeCat-Fn

spinqualitylabelsall models 5czu, resolution 1.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5czu is a 1 chain structure with sequence from Equus caballus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 4LF, CD, FE, GOL, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function FRIL_HORSE Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). Publication Abstract from PubMed A set of three catecholamide ligands mimicking the structure of enterobactin was constructed on ferritin, where the 3-fold symmetric arrangement of the monomer subunits served as a foundation to form a coordination space. Similar to enterobactin, the ligands showed strong affinity for the ferric ion and formed a tris-catechoyl complex. Crystallography revealed that the complex was embedded in the entrance of the 3-fold axis channel. Construction of an enterobactin analogue with symmetrically arranged monomer subunits of ferritin.,Nakajima H, Kondo M, Nakane T, Abe S, Nakao T, Watanabe Y, Ueno T Chem Commun (Camb). 2015 Dec 4;51(93):16609-12. doi: 10.1039/c5cc06904a. Epub, 2015 Sep 25. PMID:26404005 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Ferritin 3D structures

Proteopedia Page Contributors and Editors (what is this?)

OCA