8p3a | pdb_00008p3a

bacteriophage T5 l-alanoyl-d-glutamate peptidase Zn2+/Ca2+ form

spinqualitylabelsall models 8p3a Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8p3a is a 1 chain structure with sequence from Escherichia phage T5. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Ligands: CA, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ENLYS_BPT5 Endolysin with L-alanyl-D-glutamate peptidase activity that degrades host peptidoglycans and participates with the holin in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer by hydrolyzing the link between L-alanine and D-glutamate residues.

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