2g1z | pdb_00002g1z

X-ray structure of the oligonucleotide sequence d(AAATTT)

spinqualitylabelsall models 2g1z, resolution 3.11Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2g1z is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.11Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed We describe the packing features of the oligonucleotide duplex d(AAATTT)2, as determined by X-ray diffraction. There is little information on sequences that only contain A and T bases. The present structure confirms that these sequences tend to pack as a helical arrangement of stacked oligonucleotides in a B conformation with Watson-Crick hydrogen bonding. Our results demonstrate that the virtual TA base step between stacked duplexes has a negative twist that improves base stacking. This observation is consistent with the low stability of TA base steps in B-form DNA. Packing features of the all-AT oligonucleotide d(AAATTT).,Valls N, Santaolalla A, Campos JL, Subirana JA J Biomol Struct Dyn. 2007 Jun;24(6):547-52. PMID:17508776 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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