7y7y | pdb_00007y7y

Cryo-EM structure of human GABA transporter GAT1 bound with nipecotic acid in NaCl solution in an inward-occluded state at 2.4 angstrom

spinqualitylabelsall models 7y7y, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7y7y is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.4Å Ligands: CL, ID7, NA, NAG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease SC6A1_HUMAN Myoclonic-astatic epilepsy. The disease is caused by variants affecting the gene represented in this entry. Function SC6A1_HUMAN Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

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