7y7z | pdb_00007y7z

Cryo-EM structure of human GABA transporter GAT1 bound with tiagabine in NaCl solution in an inward-open state at 3.2 angstrom

spinqualitylabelsall models 7y7z, resolution 3.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7y7z is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.2Å Ligands: CL, NAG, TGI Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease SC6A1_HUMAN Myoclonic-astatic epilepsy. The disease is caused by variants affecting the gene represented in this entry. Function SC6A1_HUMAN Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

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