281d | pdb_0000281d
From Proteopedia
CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)
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Structural highlights
Publication Abstract from PubMedThe crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC). Structure of the A-DNA octamer d(GGCATGCC).,Nunn CM, Neidle S Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):269-73. PMID:15299929[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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