8iia | pdb_00008iia

Crystal structure of the oligomeric state of the extracellular domain of human myelin protein zero(MPZ/P0)

spinqualitylabelsall models 8iia, resolution 2.09Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8iia is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.09Å Ligands: GOL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease MYP0_HUMAN Charcot-Marie-Tooth disease type 1B;Autosomal dominant intermediate Charcot-Marie-Tooth disease with neuropathic pain;Roussy-Levy syndrome;Palmoplantar keratoderma-hereditary motor and sensory neuropathy syndrome;Autosomal dominant Charcot-Marie-Tooth disease type 2J;Autosomal dominant Charcot-Marie-Tooth disease type 2I;Autosomal dominant intermediate Charcot-Marie-Tooth disease type D;Dejerine-Sottas syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease may be caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function MYP0_HUMAN Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.

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