2nqa | pdb_00002nqa

Catalytic Domain of Human Calpain 8

spinqualitylabelsall models 2nqa, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2nqa is a 4 chain structure with sequence from Homo sapiens and Streptomyces roseus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.2Å Ligands: ACE, AR7, CA, CSO Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CAN2_HUMAN Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.CAN8_HUMAN Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Calpain 3D structures

Proteopedia Page Contributors and Editors (what is this?)

OCA