Polyl hydroxylase domain 3D structures

Updated on 13-September-2023

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• Prolyl hydroxylase domain containing Mn
  • 5l9r - hPHD2 catalytic domain residues 181-426 (mutant) + Mn + 2OG - human
    
  • 3hqr, 5l9b - hPHD2 catalytic domain (mutant) + Mn + HIF 1 α C terminal + 2OG
    
  • 5l9v, 5la9, 5las - hPHD2 catalytic domain (mutant) + Mn + HIF NODD domain + 2OG
    
  • 4bqw, 4bqx, 4bqy - hPHD2 catalytic domain + Mn + quinolin derivative
    
  • 6st3 - hPHD2 catalytic domain + Mn + pyrimidin derivative
    
  • 6yvt - hPHD2 catalytic domain + Mn + pyridin derivative
    
  • 6qgv, 5a3u, 6st3, 6yvt, 6zbn, 6zbo - hPHD2 catalytic domain + Mn + inhibitor
    
  • 5ox5, 5ox6 - hPHD2 catalytic domain + Mn + drug
    
  • 5lat, 5lb6, 5lbb, 5lbc, 5lbe, 5lbf, 4uwd - hPHD2 catalytic domain (mutant) + Mn + quinolin derivative
    
  • 6yvx, 6yvz - hPHD2 catalytic domain + Mn + peptide
    
  • 6yw3, 7q5v, 7q5x - hPHD2 catalytic domain + Mn + peptide + oxalylglycine
    
  • 6yw1, 6yw2, 6yw4 - hPHD2 catalytic domain (mutant) + Mn + peptide + oxalylglycine
    
• Prolyl hydroxylase domain containing other metal ions
  • 2y33 – hPHD2 catalytic domain residues + Zn + quinolin derivative – human
    
  • 3ouh, 3oui, 5v18, 6nmq, 6yvw, 6yw0 - hPHD2 catalytic domain + Fe + inhibitor
    
  • 4kbz - hPHD2 catalytic domain (mutant) + Fe + inhibitor
    
  • 4jzr - hPHD2 catalytic domain + Ni + inhibitor
    
  • 3ouj - hPHD2 catalytic domain + Fe + 2OG
    
  • 3hqu - hPHD2 catalytic domain + Fe + HIF 1 α C terminal + quinolin derivative
    
  • 2hbt, 2hbu, 2g19, 2g1m, 2y34, 4bqi - hPHD2 catalytic domain + Fe + quinolin derivative
    
  • 5v18 - hPHD2 catalytic domain + Fe + pyridin derivative
    
  • 5v1b - hPHD1 catalytic domain + Fe + inhibitor
    
  • 6nmq - hPHD2 catalytic domain + Fe + inhibitor
    
  • 7ump - hPHD2 catalytic domain + Fe + drug
    
  • 7ujv - hPHD2 catalytic domain + Fe + peptide + oxalylglycine
    

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Michal Harel