6udm | pdb_00006udm

Structure of Human Cytochrome P450 1A1 with Duocarmycin Prodrug (S) ICT-2726

spinqualitylabelsall models 6udm, resolution 3.08Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6udm is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.075Å Ligands: CPS, HEM, Q4P Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CP1A1_HUMAN Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

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