8fe5 | pdb_00008fe5

Structure of J-PKAc chimera complexed with Aplithianine B

spinqualitylabelsall models 8fe5, resolution 2.51Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8fe5 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.51Å Ligands: SEP, TPO, XTT Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function IPKA_HUMAN Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

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