8uw0 | pdb_00008uw0

Escherichia coli DHFR bound to NADP+ and folate, 17.2 MGy dose

spinqualitylabelsall models 8uw0, resolution 0.93Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8uw0 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 0.93Å Ligands: FOL, MN, NAP, OCS Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function C3TR70_ECOLX Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]

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